“Large-Scale” US Military Operation Destroys ISIS Positions After Troops Killed

The United States military launched a comprehensive assault on Islamic State targets across Syria, striking 70 locations in what officials termed a “large-scale” operation responding to terrorist attacks on American forces. The action demonstrated swift American retaliation capabilities and commitment to protecting personnel engaged in counter-terrorism missions.
Saturday’s deadly incident in Palmyra claimed the lives of three Americans supporting Operation Inherent Resolve, the international mission combating ISIS. Two US Army soldiers and a civilian interpreter were killed when an attacker opened fire on their convoy, while three additional service members sustained injuries. The assailant, identified as a Syrian security force member with suspected ISIS connections, was neutralized during the attack.
The retaliatory operation targeted extensive ISIS infrastructure throughout central Syria, hitting facilities used for weapons storage, training, and operational planning. Military officials indicated the strikes successfully degraded terrorist capabilities and that additional operations would follow. Defense Secretary Pete Hegseth announced the strikes with strong rhetoric, declaring America had “hunted and killed” its enemies and would continue aggressive counter-terrorism operations.
Syria’s new government under President Ahmed al-Sharaa has aligned itself with American counter-terrorism objectives, creating unprecedented bilateral cooperation. President Trump acknowledged this support, expressing hope for Syria’s future if ISIS can be eliminated. The cooperation marks a significant departure from the hostile relations that characterized the Assad era.
The American military presence in Syria remains subject to ongoing strategic review and policy discussions. While the Trump administration has historically favored reducing overseas commitments, recent events underscore continuing terrorist threats in the region. The Pentagon previously announced plans to cut personnel by half and consolidate to fewer bases, but implementation depends on security conditions. US forces currently operate from multiple locations throughout Syria, including Kurdish-controlled northeastern territories and strategic positions near Jordan, where they continue supporting international coalition efforts against terrorism. Syria’s foreign ministry has committed to preventing ISIS from establishing safe havens, affirming shared counter-terrorism objectives with international partners working to ensure regional stability.